Scientist II, High Throughput Biology

Xaira Therapeutics
Seattle, London
Workplace: OnsiteFull timeUSD 124,000 - 155,000 annuallyFunction: Research & Scientific (R&D)Experience: 2-4 yearsEducation: phdSkills: ["Analytical skills","Troubleshooting","Communication","Collaboration","Independent project management"]

Design and execute high-impact experiments to accelerate drug discovery and development using functional genomics and synthetic biology. Build and optimize biochemical, molecular, and cell-based assays for a high-throughput screening platform, scale binder discovery in mammalian systems, and develop automated workflows for reproducible, high-quality data. Partner with drug discovery, computational biology, and AI-based protein design teams, manage multiple projects, and present findings through internal and external scientific communication.

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Xaira Therapeutics
Xaira Therapeutics
3 days ago

Scientist II, High Throughput Biology

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Last checked: 8 hours agoStatus: Live

Job Summary

Design and execute high-impact experiments to accelerate drug discovery and development using functional genomics and synthetic biology. Build and optimize biochemical, molecular, and cell-based assays for a high-throughput screening platform, scale binder discovery in mammalian systems, and develop automated workflows for reproducible, high-quality data. Partner with drug discovery, computational biology, and AI-based protein design teams, manage multiple projects, and present findings through internal and external scientific communication.
Location: Seattle, London
Workplace: Onsite
Employment Type: Full time
Job Function: Research & Scientific (R&D)
Seniority: Mid level

Key Responsibilities

  • •Design, implement, and optimize biochemical, molecular, and cell-based assays for high-throughput screening platform development.
  • •Scale high-throughput screening strategies for binder discovery in mammalian systems.
  • •Evaluate and pilot emerging technologies and experimental workflows to enhance discovery capabilities.
  • •Develop and optimize automated workflows to ensure data quality, reproducibility, and process efficiency.
  • •Collaborate with drug discovery, computational biology, and AI-based protein design teams; manage multiple projects and maintain accurate experimental records.

Pay and Benefits

Salary: USD 124,000 - 155,000 annually
Equity and Bonus:Equity

Key Requirements

  • •Ph.D. in Immunology, Molecular Biology, Cell Biology, Biochemistry, Functional Genomics, or related field, with 2-4 years of postdoctoral or industry experience.
  • •Proficiency with molecular biology techniques, complex library construction, flow cytometry, and cell line engineering.
  • •Experience with pooled screening and NGS-based readouts, including library preparation and sequencing QC.
  • •Strong data analysis and troubleshooting skills, including visualization and statistical software (e.g., GraphPad Prism, R, Python).
  • •Excellent written and verbal communication skills, with the ability to present scientific findings clearly across diverse audiences.
Experience:2-4 yearsBiotechDrug discoveryFunctional genomicsSynthetic biologyHigh-throughput screeningNGS
Education:PhD / Doctorate
Skills:Analytical skillsTroubleshootingCommunicationCollaborationIndependent project management
Languages:English
Tech Stack:Functional genomicsSynthetic biologyHigh-throughput screeningFlow cytometryCell line engineeringPooled screeningNGSLibrary preparationSequencing QCYeast displayPhage displayMammalian displayScRNA-seqSingle-cell genomicsGraphPad PrismRPythonVisualizationStatistical software

Company Brief

Xaira Therapeutics
Xaira Therapeutics is a biotechnology company developing novel targeted therapeutics using proprietary discovery platforms to address serious unmet medical needs. The company focuses on advancing preclinical and clinical-stage programs toward regulatory approval and commercialization.
Industry: Biotech
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