Vice President, Investment Decisions, Rare Disease

AstraZeneca
Dublin
Workplace: OnsiteFull timeFunction: Executive & General ManagementEducation: mastersSkills: ["Strategic insight","Analytical","Communication","Influencing","Collaboration"]

Lead investment governance and decision-support for the Rare Disease portfolio, advising the CEO and Alexion Leadership Team on portfolio strategy, investment prioritisation, and long-term value creation. Serve on key governance committees and support Irish entity board engagement and compliance. Build robust business case frameworks, stress-test assumptions and scenarios, and escalate Rare Disease R&D risks and issues while partnering across scientific, operational, and financial stakeholders.

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FursaFursa
AstraZeneca
AstraZeneca
2 months ago

Vice President, Investment Decisions, Rare Disease

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Source: Company careers pageValidated by: Fursa AI
Last checked: 24 days agoStatus: Live

Job Summary

Lead investment governance and decision-support for the Rare Disease portfolio, advising the CEO and Alexion Leadership Team on portfolio strategy, investment prioritisation, and long-term value creation. Serve on key governance committees and support Irish entity board engagement and compliance. Build robust business case frameworks, stress-test assumptions and scenarios, and escalate Rare Disease R&D risks and issues while partnering across scientific, operational, and financial stakeholders.
Location: Dublin
Workplace: Onsite
Employment Type: Full time
Job Function: Executive & General Management
Seniority: Sr. Director level

Key Responsibilities

  • •Support Rare Disease therapeutic area strategy with the VP R&D and senior Alexion leaders.
  • •Lead investment governance and business case quality across key decision forums (ESPC, LSPC, rDRC, FRC).
  • •Develop and maintain decision-support frameworks for the CEO and ALT, challenging assumptions and stress-testing scenarios.
  • •Advise on long-term strategy, portfolio investment sizing, and business development or partnership opportunities with clear financial planning frameworks.
  • •Support Irish entity governance for APIO and AZIL Boards, including Board engagement and alignment with Irish legal and regulatory obligations.

Key Requirements

  • •Advanced degree in Business, Life Sciences, or related discipline; MD, PhD, or MBA strongly preferred.
  • •Significant strategic leadership experience in biopharmaceutical or life sciences, including VP-level or equivalent responsibility.
  • •Deep expertise in portfolio investment analysis and business case development across R&D and/or commercial programs.
  • •Experience advising senior executive/C-suite leaders on strategic investment decisions in a complex, matrixed environment.
  • •Strong understanding of corporate governance, Board reporting, and strategic planning.
Experience:BiopharmaceuticalLife sciences
Education:Master's
Skills:Strategic insightAnalyticalCommunicationInfluencingCollaboration

Company Brief

AstraZeneca
Global biopharmaceutical company discovering, developing and commercializing prescription medicines across oncology, cardiovascular, renal & metabolism, respiratory, and immunology, focused on innovative therapies and vaccines to improve patient outcomes worldwide.
Industry: Pharmaceuticals
Company Size: Enterprise (1,001+ employees)
Revenue: USD 1B+
Growth: Public Company
Valuation: Public Company (Market Cap in USD)
Funding: IPO / Publicly Listed
Headquarters: Cambridge, United Kingdom
Founded: 1999
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Glassdoor: 3.8
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