Research Fellow - Department of Cardiovascular Sciences - 107823 - Grade 7

University of Birmingham
United Kingdom
Workplace: OnsiteFull timeGBP 36,636 - 42,254 annuallyFunction: Research & Scientific (R&D)Education: phdSkills: ["Communication","Analytical ability","Research management","Record keeping","Presentation"]

Conduct immunology research in cardiovascular immunology to investigate mechanisms of atherosclerotic plaque instability. Characterise NK cell receptors on CD4+CD28null T cells in acute coronary syndrome, using flow cytometry, T-cell functional assays, live cell imaging, spatial transcriptomics (CosMx 6K), and multiplex proteomics/immunofluorescence (Lunaphore/COMET). Analyse complex biological and computational datasets, disseminate findings through publications and presentations, and support grant writing and research administration.

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FursaFursa
University of Birmingham
University of Birmingham
1 day ago

Research Fellow - Department of Cardiovascular Sciences - 107823 - Grade 7

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Job Summary

Conduct immunology research in cardiovascular immunology to investigate mechanisms of atherosclerotic plaque instability. Characterise NK cell receptors on CD4+CD28null T cells in acute coronary syndrome, using flow cytometry, T-cell functional assays, live cell imaging, spatial transcriptomics (CosMx 6K), and multiplex proteomics/immunofluorescence (Lunaphore/COMET). Analyse complex biological and computational datasets, disseminate findings through publications and presentations, and support grant writing and research administration.
Location: United Kingdom
Workplace: Onsite
Employment Type: Full time
Job Function: Research & Scientific (R&D)
Seniority: Mid level

Key Responsibilities

  • •Characterise the expression and roles of NK cell receptors in CD4+CD28null T cells in acute coronary syndrome.
  • •Prepare coronary artery tissue and samples for spatial transcriptomics (CosMx 6K) and multiplex immunofluorescence/proteomics workflows.
  • •Perform and assess immunology experiments including flow cytometry, PBMC/T-cell isolation, cytolytic and functional assays, and modulation using antibodies/inhibitors.
  • •Analyse spatial transcriptomics and multiplex immunofluorescence imaging data, including integration of publicly available single-cell RNA-seq datasets.
  • •Disseminate results via publications/seminars/posters and contribute to writing bids and research funding activities.

Pay and Benefits

Salary: GBP 36,636 - 42,254 annually

Key Requirements

  • •PhD degree (or near completion) relevant to immunology or a closely related field (e.g. cell biology, biomedical sciences).
  • •Strong understanding of disease pathology and cell biology underlying atherosclerosis or other immune-mediated inflammatory diseases.
  • •Strong laboratory-based immunology experience including sterile human tissue handling and culture, cell-based profiling (flow cytometry or imaging), molecular biology, and tissue staining/imaging.
  • •High analytical capability to analyse, interpret, present, and publish complex biological data in reputable journals.
  • •Excellent communication skills, including writing for publication and presenting research proposals/results.
Education:PhD / Doctorate
Skills:CommunicationAnalytical abilityResearch managementRecord keepingPresentation
Tech Stack:Flow cytometryImagingMicroscopySpatial transcriptomicsCosMx 6KMultiplex proteomicsImmunofluorescenceLunaphoreCOMETRPythonLinux command lineSingle-cell RNA sequencingTranscriptomics

Company Brief

University of Birmingham
A major UK research university offering undergraduate, postgraduate, and doctoral programs across a wide range of disciplines; known for research, teaching excellence, and international partnerships.
Industry: Higher Education
Company Size: Enterprise (1,001+ employees)
Revenue: USD 500M to 1B
Growth: Government & Public Sector
Funding: Government Funded
Headquarters: Birmingham, United Kingdom
Founded: 1900
WebsiteLinkedIn