1 day ago

Senior Scientist, Functional Genomics

✓ Verified Job

Canonical indexed version, validated from employer's careers page.

Source: Company careers pageValidated by: Fursa AI

Last checked: 22 hours agoStatus: Live

Job Summary

Architect and lead in vivo CRISPR screening efforts to advance high-throughput functional genomics. Develop and scale screening protocols in mouse models, drive innovation in experimental workflows, and troubleshoot data-generation challenges such as reproducibility, throughput, and quality control. Partner with computational biology and AI/ML teams to analyze, interpret, visualize, and communicate results from large datasets, while managing multiple projects and mentoring junior staff.

Location: United States

Workplace: Onsite

Employment Type: Full time

Job Function: Research & Scientific (R&D)

Seniority: Mid level

Key Responsibilities

•Develop, implement, and scale high-throughput CRISPR-based screening protocols in mouse models to uncover genotype-phenotype relationships at scale.
•Drive continuous innovation in experimental workflows and screening methodologies.
•Analyze, interpret, visualize, and communicate findings from large-scale functional genomics datasets in partnership with computational biology, AI/ML, and drug discovery teams.
•Identify and resolve challenges in data generation, including assay reproducibility, sample throughput, and quality control.
•Manage multiple projects to ensure timely delivery of high-quality data; mentor junior staff and lead cross-functional collaboration milestones.

Pay and Benefits

Salary: USD 136,000 - 170,000 annually

Equity and Bonus:Equity

Key Requirements

•Ph.D. in Molecular Biology, Genetics, Pharmacology, or related field with 4+ years of postdoctoral or industry experience.
•Strong in vivo genetic manipulation experience (e.g., lentiviral or AAV delivery in mice) including mouse handling, colony management, and animal welfare/regulatory standards.
•Familiarity with perturb-seq and single-cell genomics.
•Ability to troubleshoot technical issues, adapt to new protocols, and optimize in vivo applications.
•Excellent written and verbal communication; ability to present complex scientific results to multidisciplinary teams.

Experience:4+ yearsBiotechDrug discoveryIn vivoGenomicsCRISPRSingle-cell genomics

Education:PhD / Doctorate

Skills:CommunicationProblem-solvingCollaborationMentoringProject management

Languages:English

Tech Stack:CRISPRIn vivo genetic manipulationLentiviral deliveryAAV deliveryMouse modelsPerturb-seqSingle-cell genomicsPythonRAI/MLComputational biologyData analysisQuality controlExperimental workflows

Company Brief

Xaira Therapeutics

Xaira Therapeutics is a biotechnology company developing novel targeted therapeutics using proprietary discovery platforms to address serious unmet medical needs. The company focuses on advancing preclinical and clinical-stage programs toward regulatory approval and commercialization.

Industry: Biotech

Website

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Xaira Therapeutics

1 day ago

Senior Scientist, Functional Genomics

✓ Verified Job

Canonical indexed version, validated from employer's careers page.

Source: Company careers pageValidated by: Fursa AI

Last checked: 22 hours agoStatus: Live

Job Summary

Location: United States

Workplace: Onsite

Employment Type: Full time

Job Function: Research & Scientific (R&D)

Seniority: Mid level

Key Responsibilities

•Develop, implement, and scale high-throughput CRISPR-based screening protocols in mouse models to uncover genotype-phenotype relationships at scale.
•Drive continuous innovation in experimental workflows and screening methodologies.
•Analyze, interpret, visualize, and communicate findings from large-scale functional genomics datasets in partnership with computational biology, AI/ML, and drug discovery teams.
•Identify and resolve challenges in data generation, including assay reproducibility, sample throughput, and quality control.
•Manage multiple projects to ensure timely delivery of high-quality data; mentor junior staff and lead cross-functional collaboration milestones.

Pay and Benefits

Salary: USD 136,000 - 170,000 annually

Equity and Bonus:Equity

Key Requirements

•Ph.D. in Molecular Biology, Genetics, Pharmacology, or related field with 4+ years of postdoctoral or industry experience.
•Strong in vivo genetic manipulation experience (e.g., lentiviral or AAV delivery in mice) including mouse handling, colony management, and animal welfare/regulatory standards.
•Familiarity with perturb-seq and single-cell genomics.
•Ability to troubleshoot technical issues, adapt to new protocols, and optimize in vivo applications.
•Excellent written and verbal communication; ability to present complex scientific results to multidisciplinary teams.

Experience:4+ yearsBiotechDrug discoveryIn vivoGenomicsCRISPRSingle-cell genomics

Education:PhD / Doctorate

Skills:CommunicationProblem-solvingCollaborationMentoringProject management

Languages:English

Company Brief

Xaira Therapeutics

Industry: Biotech

Website