Staff Senior Systems Engineer, OT

Lila Sciences
Cambridge
Workplace: OnsiteFull timeUSD 140,000 - 186,667 annuallyFunction: Solutions Engineering & Sales EngineeringSkills: ["Communication","Risk decision-making","Technical documentation","Autonomy"]

Own hands-on OT security engineering for autonomous laboratory environments, translating OT security architecture into operational controls across segmentation, identity, privileged access, vendor access, monitoring, detection, response, and lifecycle management. Design and validate IEC 62443-aligned zone-and-conduit segmentation, threat model instruments and automation platforms, lead technical sign-offs, and partner with SOC/detection teams to build OT-specific runbooks and incident response exercises.

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Lila Sciences
Lila Sciences
1 month ago

Staff Senior Systems Engineer, OT

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Source: Company careers pageValidated by: Fursa AI
Last checked: 3 hours agoStatus: Live

Job Summary

Own hands-on OT security engineering for autonomous laboratory environments, translating OT security architecture into operational controls across segmentation, identity, privileged access, vendor access, monitoring, detection, response, and lifecycle management. Design and validate IEC 62443-aligned zone-and-conduit segmentation, threat model instruments and automation platforms, lead technical sign-offs, and partner with SOC/detection teams to build OT-specific runbooks and incident response exercises.
Location: Cambridge
Workplace: Onsite
Employment Type: Full time
Job Function: Solutions Engineering & Sales Engineering
Seniority: Mid level

Key Responsibilities

  • •Translate OT security architecture into operational controls across segmentation, identity, privileged access, detection, response, and vendor access.
  • •Design and validate zone-and-conduit segmentation aligned to IEC 62443, including security level targets and compensating controls.
  • •Develop OT-specific threat models and translate findings into design and rollout decisions.
  • •Own security reviews and technical sign-off for new automation platforms, vendor integrations, and laboratory deployments.
  • •Lead OT vulnerability and lifecycle management, and partner with SOC/detection teams to build OT-specific detection content, runbooks, escalation paths, and incident response exercises.

Pay and Benefits

Salary: USD 140,000 - 186,667 annually
Equity and Bonus:Equity
Perks:Health InsuranceDentalVisionLife InsuranceDisability InsurancePaid ParentalLearning BudgetCommuter BenefitsMeal Allowance

Key Requirements

  • •Significant hands-on cybersecurity or OT security engineering experience in operationally constrained environments.
  • •Design and implement security controls in OT/industrial control systems, laboratory automation, manufacturing, or similar environments.
  • •Strong knowledge of segmentation, identity, access control, compensating controls, and secure remote access patterns.
  • •Hands-on experience in one or more OT security domains such as machine identity, PKI, privileged access management, OT monitoring, detection engineering, vulnerability management, or incident response.
  • •Solid networking and segmentation fundamentals, including VLANs, firewall policy, TCP/IP, DNS, and DHCP, with ability to translate architecture into operating controls and runbooks.
Experience:Industrial control systemsLaboratory automationManufacturingLife sciencesBiotechnologyPharmaceuticalHigh-throughput research
Skills:CommunicationRisk decision-makingTechnical documentationAutonomy
Certifications:GICSPIEC 62443 Cybersecurity ExpertGIAC GRIDGCIHCISSP
Languages:English
Tech Stack:IEC 62443VLANsFirewall policyTCP/IPDNSDHCPPacket analysisMachine identityPKITLSMTLSTPM-bound credentialsCertificate lifecycle managementPrivileged access managementIncident responseOT monitoringTelemetryClarotyTenable OTDragos

Company Brief

Lila Sciences
Develops AI-driven platforms to accelerate drug discovery and biological research by integrating machine learning with chemical and biological data to predict molecular properties, streamline candidate selection, and enable faster therapeutic development.
Industry: Biotech
Company Size: Small (11 to 50 employees)
Growth: Early Stage Startup
Funding: Seed
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