Relation

2 weeks ago

Snr Scientist II / Principal Scientist, In Vivo Biology & Translational Science

✓ Verified Job

Canonical indexed version, validated from employer's careers page.

Source: Company careers pageValidated by: Fursa AI

Last checked: 4 hours agoStatus: Live

Job Summary

Lead in vivo pharmacology strategy and study execution across Relation’s discovery programmes, partnering with CROs and cross-functional teams to design, commission, interpret, and report in vivo PK/PD and efficacy work packages. You’ll translate data into actionable project decisions, commission supportive in vitro/ex vivo assays, and manage end-to-end CRO relationships, documentation, and stakeholder communication within a TechBio, interdisciplinary environment in London.

Location: London

Workplace: Onsite

Employment Type: Full time

Job Function: Research & Scientific (R&D)

Seniority: Mid level

Key Responsibilities

•Lead in vivo pharmacology strategy, proposing study designs to support go/no-go decisions and milestone planning across concurrent projects.
•Drive execution, monitoring, and interpretation of in vivo pharmacology studies across target engagement, PK/PD, and disease-relevant efficacy endpoints.
•Own end-to-end CRO relationships for outsourced in vivo work packages, including vendor selection, SOW setup, liaison, troubleshooting, and reporting.
•Commission in vivo-relevant in vitro and ex vivo assays (e.g., target engagement, pharmacodynamic, and mechanistic readouts) to inform study decisions.
•Translate biology data into actionable insights and recommendations, maintaining rigorous documentation standards and effectively communicating with project teams and senior stakeholders.

Key Requirements

•PhD in Biology, Pharmacology, Biochemistry, or related field, or equivalent industrial drug discovery experience.
•Deep expertise in mammalian in vivo study design across target engagement, PK/PD, and efficacy endpoints, including 3Rs principles.
•Experience commissioning or interpreting in vitro and ex vivo assays supporting in vivo programmes (e.g., pharmacodynamic and mechanistic readouts).
•Experience across multiple stages of drug discovery (target ID through candidate selection) and across more than one disease area or physiological system.
•Strong analytical mindset with proven communication and stakeholder management skills to influence cross-functional decisions.

Experience:Drug discoveryTechBioAI-driven discoveryCRO partnershipsIn vivo pharmacologyTranslational science

Education:PhD / Doctorate in Biology, Pharmacology, Biochemistry (or related scientific discipline)

Skills:Analytical thinkingCommunicationStakeholder managementScientific rigorOwnership

Tech Stack:Single-cell multi-omicsMachine learningELNCRO partnerships

Company Brief

Relation

Relation (Relation Therapeutics) is a UK-based, technology-enabled biopharmaceutical company that combines single-cell multi-omics, patient-derived tissue, functional assays and machine learning to discover and develop novel therapeutics across immunology, metabolic and bone diseases.

Industry: Biotech

Company Size: Medium (51 to 250 employees)

Growth: Early Stage Startup

Valuation: USD 100M to 250M

Funding: Seed

Headquarters: London, United Kingdom

Founded: 2019

Glassdoor: 3.8

Website LinkedIn Glassdoor

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Relation

2 weeks ago

Snr Scientist II / Principal Scientist, In Vivo Biology & Translational Science

✓ Verified Job

Canonical indexed version, validated from employer's careers page.

Source: Company careers pageValidated by: Fursa AI

Last checked: 4 hours agoStatus: Live

Job Summary

Location: London

Workplace: Onsite

Employment Type: Full time

Job Function: Research & Scientific (R&D)

Seniority: Mid level

Key Responsibilities

•Lead in vivo pharmacology strategy, proposing study designs to support go/no-go decisions and milestone planning across concurrent projects.
•Drive execution, monitoring, and interpretation of in vivo pharmacology studies across target engagement, PK/PD, and disease-relevant efficacy endpoints.
•Own end-to-end CRO relationships for outsourced in vivo work packages, including vendor selection, SOW setup, liaison, troubleshooting, and reporting.
•Commission in vivo-relevant in vitro and ex vivo assays (e.g., target engagement, pharmacodynamic, and mechanistic readouts) to inform study decisions.
•Translate biology data into actionable insights and recommendations, maintaining rigorous documentation standards and effectively communicating with project teams and senior stakeholders.

Key Requirements

•PhD in Biology, Pharmacology, Biochemistry, or related field, or equivalent industrial drug discovery experience.
•Deep expertise in mammalian in vivo study design across target engagement, PK/PD, and efficacy endpoints, including 3Rs principles.
•Experience commissioning or interpreting in vitro and ex vivo assays supporting in vivo programmes (e.g., pharmacodynamic and mechanistic readouts).
•Experience across multiple stages of drug discovery (target ID through candidate selection) and across more than one disease area or physiological system.
•Strong analytical mindset with proven communication and stakeholder management skills to influence cross-functional decisions.

Experience:Drug discoveryTechBioAI-driven discoveryCRO partnershipsIn vivo pharmacologyTranslational science

Education:PhD / Doctorate in Biology, Pharmacology, Biochemistry (or related scientific discipline)

Skills:Analytical thinkingCommunicationStakeholder managementScientific rigorOwnership

Tech Stack:Single-cell multi-omicsMachine learningELNCRO partnerships

Company Brief

Relation

Industry: Biotech

Company Size: Medium (51 to 250 employees)

Growth: Early Stage Startup

Valuation: USD 100M to 250M

Funding: Seed

Headquarters: London, United Kingdom

Founded: 2019

Glassdoor: 3.8

Website LinkedIn Glassdoor