Bioengineer / Molecular Biologist

Adaptyv
Switzerland
Workplace: OnsiteFull timeFunction: Data Analytics & Business IntelligenceEducation: phdSkills: ["Rigorous experimentalist","Data analysis","Troubleshooting","Independent","Resourceful"]

Work hands-on in Adaptyv’s biology and production team to develop and optimize protein expression workflows across cell-free (PURE, lysate-based), E. coli, and potentially mammalian systems. Design and execute DNA synthesis and assembly protocols (PCR, Golden Gate, Gibson), run molecular biology experiments at the bench, and characterize proteins using BLI, SPR, and enzymatic assays. Analyze experimental data to diagnose failure modes and improve methods, and collaborate with the automation team to translate protocols into automated workflows.

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Adaptyv
Adaptyv
2 months ago

Bioengineer / Molecular Biologist

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Last checked: 19 hours agoStatus: Live

Job Summary

Work hands-on in Adaptyv’s biology and production team to develop and optimize protein expression workflows across cell-free (PURE, lysate-based), E. coli, and potentially mammalian systems. Design and execute DNA synthesis and assembly protocols (PCR, Golden Gate, Gibson), run molecular biology experiments at the bench, and characterize proteins using BLI, SPR, and enzymatic assays. Analyze experimental data to diagnose failure modes and improve methods, and collaborate with the automation team to translate protocols into automated workflows.
Location: Switzerland
Workplace: Onsite
Employment Type: Full time
Job Function: Data Analytics & Business Intelligence

Key Responsibilities

  • •Develop and optimize protein expression workflows (cell-free PURE and lysate-based, E. coli, and potentially mammalian systems) and troubleshoot expression issues.
  • •Design and execute DNA synthesis and assembly protocols (PCR, Golden Gate, Gibson) to improve yield, fidelity, and throughput.
  • •Develop or adapt assays for thermostability, developability, enzyme activity, and other platform needs.
  • •Run experiments at the bench, analyze results, and iteratively improve protocols (not a project management role).
  • •Translate methods into automated workflows with the automation team, diagnose failure modes, and improve methods systematically.

Key Requirements

  • •MSc or PhD in molecular biology, biochemistry, bioengineering, or a related field; hands-on bench experience is emphasized.
  • •Practical protein expression and purification experience, including producing soluble, folded, functional recombinant proteins.
  • •Experience with DNA synthesis, cloning, or assembly methods (PCR, Golden Gate, Gibson); high-throughput experience is a plus.
  • •Comfort analyzing experimental data such as chromatograms, binding curves, and expression gels.
  • •Interest in automation and a rigorous experimental approach with proper controls and reproducibility.
Education:PhD / Doctorate
Skills:Rigorous experimentalistData analysisTroubleshootingIndependentResourceful
Tech Stack:PCRGolden GateGibsonPUREE. coliBLISPR

Company Brief

Adaptyv
Biotechnology company developing adaptive immunotherapy platforms and precision biologic treatments aimed at enhancing immune responses against disease. Focuses on engineering biologic solutions and translational research to accelerate therapeutic candidates from discovery to clinical development.
Industry: Biotech
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