Xaira Therapeutics

1 day ago

Scientist II, Display Technologies

✓ Verified Job

Canonical indexed version, validated from employer's careers page.

Source: Company careers pageValidated by: Fursa AI

Last checked: 17 hours agoStatus: Live

Job Summary

Own end-to-end phage display campaigns in the Display Technologies group, driving target selection, panning, and hit validation for both soluble antigens and challenging membrane proteins. Build and optimize display libraries using core molecular biology methods, and run clonal affinity/functional characterization with FACS, ELISA, and SPR. Partner with computational and ML teams to generate high-quality training data, while mentoring associate scientists and setting technical standards.

Location: United States

Workplace: Onsite

Employment Type: Full time

Job Function: Research & Scientific (R&D)

Key Responsibilities

•Independently design, execute, and own phage display campaigns from library through panning and hit validation for soluble antigens and membrane-protein targets.
•Develop and optimize selection strategies, including troubleshooting antigen production, presentation, and quality control.
•Design and build display libraries using molecular biology fundamentals (cloning, mutagenesis, assembly) to generate high-quality, diverse repertoires.
•Design and run clonal-level affinity and functional characterization using FACS, ELISA, and SPR, and help adapt assays for higher-throughput/automation.
•Partner with computational and ML colleagues to generate, structure, and quality-control data at scale; mentor associate scientists and contribute to technical reporting and documentation.

Pay and Benefits

Salary: USD 124,000 - 155,000 annually

Key Requirements

•PhD in Molecular Biology, Biochemistry, Immunology, Protein Engineering, or related field, with 2–4 years of relevant industry experience.
•Hands-on expertise with antibody/protein discovery by phage display, including library design, build, panning/selection, and hit validation.
•Strong molecular biology skills for library construction, including cloning, mutagenesis, and assembly to generate diverse repertoires.
•Required: hands-on flow cytometry (FACS) experience, including data interpretation and gating strategy.
•Experience running campaigns independently and troubleshooting challenging targets; membrane protein experience (e.g., GPCRs) is strongly preferred.

Experience:2-4 yearsBiotechDrug discoveryPhage displayAntibody discoveryProtein engineering

Education:PhD / Doctorate in Molecular Biology, Biochemistry, Immunology, Protein Engineering

Skills:AnalyticalProblem-solvingAttention to detailCommunicationCollaborationMentorship

Languages:English

Tech Stack:Phage displayPanningHit validationLibrary designCloningMutagenesisAssemblyFlow cytometryFACSELISASPRCell-based expression systemsRecombinant formatsGPCRMammalian cell cultureLabel-free affinity characterizationBLIOctetLab automationHamilton

Company Brief

Xaira Therapeutics

Xaira Therapeutics is a biotechnology company developing novel targeted therapeutics using proprietary discovery platforms to address serious unmet medical needs. The company focuses on advancing preclinical and clinical-stage programs toward regulatory approval and commercialization.

Industry: Biotech

Website

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Xaira Therapeutics

1 day ago

Scientist II, Display Technologies

✓ Verified Job

Canonical indexed version, validated from employer's careers page.

Source: Company careers pageValidated by: Fursa AI

Last checked: 17 hours agoStatus: Live

Job Summary

Location: United States

Workplace: Onsite

Employment Type: Full time

Job Function: Research & Scientific (R&D)

Key Responsibilities

•Independently design, execute, and own phage display campaigns from library through panning and hit validation for soluble antigens and membrane-protein targets.
•Develop and optimize selection strategies, including troubleshooting antigen production, presentation, and quality control.
•Design and build display libraries using molecular biology fundamentals (cloning, mutagenesis, assembly) to generate high-quality, diverse repertoires.
•Design and run clonal-level affinity and functional characterization using FACS, ELISA, and SPR, and help adapt assays for higher-throughput/automation.
•Partner with computational and ML colleagues to generate, structure, and quality-control data at scale; mentor associate scientists and contribute to technical reporting and documentation.

Pay and Benefits

Salary: USD 124,000 - 155,000 annually

Key Requirements

•PhD in Molecular Biology, Biochemistry, Immunology, Protein Engineering, or related field, with 2–4 years of relevant industry experience.
•Hands-on expertise with antibody/protein discovery by phage display, including library design, build, panning/selection, and hit validation.
•Strong molecular biology skills for library construction, including cloning, mutagenesis, and assembly to generate diverse repertoires.
•Required: hands-on flow cytometry (FACS) experience, including data interpretation and gating strategy.
•Experience running campaigns independently and troubleshooting challenging targets; membrane protein experience (e.g., GPCRs) is strongly preferred.

Experience:2-4 yearsBiotechDrug discoveryPhage displayAntibody discoveryProtein engineering

Education:PhD / Doctorate in Molecular Biology, Biochemistry, Immunology, Protein Engineering

Skills:AnalyticalProblem-solvingAttention to detailCommunicationCollaborationMentorship

Languages:English

Company Brief

Xaira Therapeutics

Industry: Biotech

Website